Invited Speakers

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Invited Speakers:Edit I BuzasRossella CrescitelliRiccardo AlessandroBernd GiebelDolores Di Vizio

Edit IBuzas

Edit I Buzás MD, PhD and DSc is Professor and Chair at the Department of Genetics, Cell- and Immunobiology at Semmelweis University, Budapest, Hungary. She is the PI of the HCEMM-SU and the ELKH-SE Immune-Proteogenomics Research Groups, she is Corresponding Member of the Hungarian Academy of Sciences and Member of the Academia Europaea. Her group has shown first that extracellular vesicles (EVs) and protein aggregates share biophysical parameters, and that EVs associate with glycosidase enzymes. Her group introduced differential detergent lysis, SPV lipid assay and determination of protein to lipid ratio to EV research. She is Secretary General of ISEV, Associate Editor of the Journal of Extracellular Vesicles, co-Vice Chair of the Gordon Research Conference on Extracellular Vesicles (2022). She served as Chair of ISEV2016, Rotterdam, The Netherlands.

Rossella Crescitelli

Rossella Crescitelli is a senior researcher at Sahlgrenska Center for Cancer Research, University of Gothenburg, Sweden in Roger Olofsson Bagge´s group. She is a medical biotechnologist with background in molecular biology applied at extracellular vesicles field. She has eleven years of experience in extracellular vesicle research. Graduated in Medical biotechnology at University of Naples, Italy, she moved in North of Italy at the University of Eastern Piedmont “Amedeo Avogadro”, Novara, in 2010 where she approached at extracellular vesicle field. Her PhD research was mainly focused on analysis of extracellular vesicles in blood of patients affected by Diamond Blackfan Anemia: a congenital erythroid aplasia. During her PhD, she has been invited to join the Jan Lötvall´s lab, one of the most important group in the field of extracellular vesicles where her focus was to properly separate subpopulations of extracellular vesicles and analyze their different molecular characteristics. The results were published on Journal of Extracellular Vesicles and the paper was the most cited in 2014 among the articles published on that journal and it received more than 600 citations. She continued to work in Jan Lötvall´s group as post doc fellow and the main focus was to optimize a centrifugation-based protocol to isolate vesicles directly from melanoma tumor tissues and. The protocol has been recently descripted in Nature Protocols.

Riccardo Alessandro

Riccardo Alessandro: è docente di I Fascia di Biologia e Genetica e coordinatore del Corso di Laurea Magistrale in Biotecnologie Mediche e Medicina Molecolare presso l’Università degli Studi di Palermo; dal 2015 al 2018 è stato Direttore del Dip.to di Biomedicina e Biotecnologie Mediche della stessa Università. Sin dalla sua laurea in Scienze Biologiche nel 1987 si è occupato di biologia cellulare della progressione tumorale con ricerche che hanno prodotto diverse pubblicazioni come primo, ultimo o autore corrispondente su riviste scientifiche con elevato Impact Factor, quali Proceedings of the National Academy of Sciences; Mol. Biol. Cell; Journal of Hematol. Oncology; Theranostics; J.Extracell. Vesicl. Dal 2012 si è interessato di comprendere il ruolo biologico delle vescicole extracellulari rilasciate da cellule tumorali nel processo metastatico focalizzando l’attività di ricerca sulla modulazione del microambiente tumorale utilizzando modelli in vitro ed in vivo di Leucemia Mieloide Cronica, Multiplo Mieloma, Carcinoma del Colon, del Polmone e Carcinoma Epatico. Negli ultimi anni ha allargato il campo di azione, svolgendo ricerche anche nel mondo vegetale e, per la prima volta in Italia, ha identificato e caratterizzato le vescicole presenti nel succo di limone, dimostrando la loro attività anti-infiammatoria ed anti-tumorale. Queste ultime ricerche, sono state di stimolo per fondare insieme a componenti del gruppo di ricerca, una startup, Navhetec srl, che ha collaborato ad una sperimentazione clinica di un preparato di vescicole di limone in pazienti affetti da Sindrome Metabolica i cui risultati sono stati oggetto di recente pubblicazione sulla rivista Metabolites.  Le sue ricerche sono finanziate dall’AIRC, MISE, MIUR, ARPA.

Bernd Giebel

Bernd Giebel studied biology at the University zu Köln and received his PhD in 1996. 1999 he moved to the Heinrich-Heine-University of Düsseldorf, started to work with human hematopoietic stem and progenitor cells and set up his own group. In 2008 he moved to the University Hospital Essen and continued his studies on human somatic stem cells. In 2009, as a 2nd topic his group started to work with EVs, setting a focus on mesenchymal stem/stromal cell-derived EVs (MSC-EVs). Together with collaboration partners the group demonstrated the therapeutic potential of prepared MSC-EVs in a human GvHD-patient and in different animal models. It is the goal to optimize the MSC-EV production and characterization process to efficiently translate MSC-EVs into the clinics. He is the president of the German Society of Extracellular Vesicles (GSEV), co-chairing the exosome working of the group of the International Society of Gene and Cell Therapy (ISCT) and part of the scientific advisory board of two SME companies, Innovex Therapeutics and Mursla LTD. In 2021 he became one of the two founding directors of Exosla LTD.

Publications:
https://www.ncbi.nlm.nih.gov/pubmed/?term=%22Giebel+B%22+or+%22Giebel+Bernd%22+not+%22Giebel+BM%22+not+%22J+Stem+Cells+Regen+Med%22

Dolores Di Vizio

Dolores Di Vizio is a molecular pathologist, and a molecular and cell biologist, with 20 years of experience on urological cancer. Currently she is a Professor at Cedars-Sinai Medical Center. She published over 110 peer-reviewed manuscripts, including in high impact journals (Cancer Cell, Cell, Cancer Research, Nat Med, Nat Cell Biol,) and made important contributions to cancer research in a number of areas. Her work has been cited over 10,000 times and her H-index is 56. 
While funded by a K99-R00 grant from the NCI, she discovered the large oncosome (LO), a type of extracellular vesicle (EV) that is considerably larger than exosomes and is tumor-specific. Her team has emerged as a leading group in studies of cancer EV. She sits on several grant study sections including from the NIH and the DoD. She serves as senior board member of the International Society of Extracellular Vesicles (ISEV), and is an associate editor for the Journal of Extracellular Vesicles. 

Italian Society for Extracellular Vesicles - EVIta

About EVIta Symposium

20-22 September    

2nd EVIta Symposium


 

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